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科学家成功利用非生命生物组分,从零开始构建出一个能够生长、复制DNA并分裂的合成细胞,这是合成生物学领域的一项重大突破。明尼苏达大学的合成生物学家凯特·阿达马拉(Kate Adamala)带领团队,将脂质体、DNA复制系统及特殊的膜蛋白结合,实现了人工细胞的自主分裂,展示了细胞周期的基本功能。

尽管这项技术取得了突破性进展,该合成细胞目前仍不具备完全的生命特征。它无法在没有外部持续供应食物、核糖体等关键物质的情况下生存,且其遗传变异是由人工合成引入而非自然突变产生,因此尚未实现真正的自发演化。

此项研究不仅为探索生命的起源和最低生存条件提供了新的实验途径,也为未来生产生物燃料、药物或新材料奠定了基础。此外,研究团队已成立非营利组织Biotic,将公开其数据与方法,以推动全球合成生物学的合作与发展。

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Scientists have successfully constructed a synthetic cell from scratch using nonliving biological components that can grow, replicate DNA, and divide, marking a major breakthrough in synthetic biology. Led by Kate Adamala at the University of Minnesota, the team combined liposomes, a DNA replication system, and membrane-bending proteins to achieve autonomous cell division, demonstrating the fundamental functions of a cell cycle.

Despite this groundbreaking progress, the synthetic cell is not yet fully alive. It cannot survive without constant external deliveries of food and ribosomes, and its genetic variations were introduced synthetically rather than through natural mutations, meaning it has not yet achieved true adaptive evolution.

This research not only provides a new experimental pathway to explore the origins and minimum requirements of life, but also lays the foundation for future production of biofuels, drugs, or new materials. Additionally, the research team has established a nonprofit organization called Biotic to share their data and methods, fostering global collaboration and development in synthetic biology.
2026-07-05 (Sunday) · 81f0a256b371170d70e75be357558e9f12067316