脑机介面新创 Science Corporation（2021 年由前 Neuralink 总裁 Max Hodak 创立）在 2025 年 12 月 17 日公布原型，成立新部门投入器官灌流保存。目标是把目前笨重、昂贵、主要在医院使用的灌流/生命支持设备，做成更小、更可携、可提供更长期支持的系统，用于移植器官保存与重症患者维持循环与氧合。

Hodak 的动机来自一名 17 岁囊性纤维化患者：在等候移植期间以 ECMO 维持生命，但等待约 2 个月后出现并发症而失去移植资格，最终在氧合器失效且未更换后死亡。ECMO 在新冠期间常用，但运行费用可达每天数千美元、需大量人力与持续手动调整，且并非每家医院都具备。

移植器官灌流同样成本高：TransMedics 的系统机器约 25 万美元，每次使用约 4 万到 8 万美元，远距运送甚至用其私人喷射机队。Science 表示自研系统已让兔肾离体存活最长 48 小时，目标在明年春季延长到 1 个月；人类肾脏冰存离体约 24–36 小时，而现有灌流可延长到 4 天或更久。公司约 170 名员工，累计融资约 2.9 亿美元，原型整合即时感测（血氧、流量、压力、温度）与闭回路自动调节，主打降低对专门人员的依赖并压低价格。

Science Corporation, a brain-computer interface startup founded in 2021 by former Neuralink president Max Hodak, unveiled an organ-perfusion prototype on December 17, 2025. It is launching a new division to extend how long human organs can be sustained outside the body, aiming for smaller, more portable systems than today’s clunky, costly hospital-based perfusion and life-support setups used for transplants and for patients whose hearts or lungs fail.

Hodak cites a 17-year-old cystic fibrosis patient supported by ECMO while awaiting a transplant: after roughly two months on the waitlist, complications made him ineligible, the oxygenator began failing, and he died after it was not replaced. ECMO proved vital during Covid-19 but can cost thousands of dollars per day, demands intensive staffing, constant monitoring, and frequent manual adjustments, and is not available at every hospital.

Transplant perfusion is also expensive: TransMedics’ organ care system costs about $250,000 for the machine plus roughly $40,000–$80,000 per use, with long-distance transport sometimes handled by its private-jet fleet. Science says its scratch-built system has kept rabbit kidneys alive ex vivo for up to 48 hours and targets a month by next spring; human kidneys on ice last about 24–36 hours, while existing perfusion can extend viability to four days or more. With ~170 employees and about $290 million raised, Science emphasizes integrated real-time sensors (oxygenation, flow, pressure, temperature) and closed-loop automation to reduce manual control and drive costs down.